Sumoylation regulates the assembly and activity of the SMN complex

SMN is a ubiquitously expressed protein and is essential for life. SMN deficiency causes the neurodegenerative disease spinal muscular atrophy (SMA), the leading genetic cause of infant mortality. SMN interacts with itself and other proteins to form a complex that functions in the assembly of ribonu...

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Detalles Bibliográficos
Autores principales: Riboldi, Giulietta M., Faravelli, Irene, Kuwajima, Takaaki, Delestrée, Nicolas, Dermentzaki, Georgia, De Planell-Saguer, Mariangels, Rinchetti, Paola, Hao, Le Thi, Beattie, Christine C., Corti, Stefania, Przedborski, Serge, Mentis, George Z., Lotti, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376998/
https://www.ncbi.nlm.nih.gov/pubmed/34413305
http://dx.doi.org/10.1038/s41467-021-25272-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376998/
https://www.ncbi.nlm.nih.gov/pubmed/34413305
http://dx.doi.org/10.1038/s41467-021-25272-5

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