Cargando…

BMP antagonists in tissue development and disease

Bone morphogenic proteins (BMPs) are important growth regulators in embryogenesis and postnatal homeostasis. Their tight regulation is crucial for successful embryonic development as well as tissue homeostasis in the adult organism. BMP inhibition by natural extracellular biologic antagonists repres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Correns, Annkatrin, Zimmermann, Laura-Marie A., Baldock, Clair, Sengle, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377005/ https://www.ncbi.nlm.nih.gov/pubmed/34435185 http://dx.doi.org/10.1016/j.mbplus.2021.100071

Ejemplares similares

Internal cleavage and synergy with twisted gastrulation enhance BMP inhibition by BMPER
por: Lockhart-Cairns, Michael P., et al.
Publicado: (2019)

The role of chordin fragments generated by partial tolloid cleavage in regulating BMP activity
por: Troilo, Helen, et al.
Publicado: (2015)

Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway
por: Troilo, Helen, et al.
Publicado: (2016)

Extracellular Regulation of Bone Morphogenetic Protein Activity by the Microfibril Component Fibrillin-1
por: Wohl, Alexander P., et al.
Publicado: (2016)

BMPER Improves Vascular Remodeling and the Contractile Vascular SMC Phenotype
por: Pankratz, Franziska, et al.
Publicado: (2023)

Synthetic enzyme-substrate tethering obviates the Tolloid-ECM interaction during Drosophila BMP gradient formation
por: Winstanley, Jennifer, et al.
Publicado: (2015)

ADAMTS10-mediated tissue disruption in Weill–Marchesani syndrome
por: Mularczyk, Ewa J, et al.
Publicado: (2018)

R-spondins are BMP receptor antagonists in Xenopus early embryonic development
por: Lee, Hyeyoon, et al.
Publicado: (2020)

Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice
por: Sengle, Gerhard, et al.
Publicado: (2015)

Expression and Functional Study of Extracellular BMP Antagonists during the Morphogenesis of the Digits and Their Associated Connective Tissues
por: Lorda-Diez, Carlos I., et al.
Publicado: (2013)

Fibrillin microfibril structure identifies long-range effects of inherited pathogenic mutations affecting a key regulatory latent TGFβ-binding site
por: Godwin, Alan R. F., et al.
Publicado: (2023)

Publisher Correction: Fibrillin microfibril structure identifies long-range effects of inherited pathogenic mutations affecting a key regulatory latent TGFβ-binding site
por: Godwin, Alan R. F., et al.
Publicado: (2023)

The Role of the BMP Signaling Antagonist Noggin in the Development of Prostate Cancer Osteolytic Bone Metastasis
por: Secondini, Chiara, et al.
Publicado: (2011)

The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses
por: Ichinose, Mari, et al.
Publicado: (2021)

Editorial: Molecular Mechanisms of Heritable Connective Tissue Disorders
por: Malfait, Fransiska, et al.
Publicado: (2022)

Gremlin-2 is a BMP antagonist that is regulated by the circadian clock
por: Yeung, Ching-Yan Chloé, et al.
Publicado: (2014)

Extracellular BMP Antagonists, Multifaceted Orchestrators in the Tumor and Its Microenvironment
por: Ouahoud, Sarah, et al.
Publicado: (2020)

Twisted Gastrulation, a BMP Antagonist, Exacerbates Podocyte Injury
por: Yamada, Sachiko, et al.
Publicado: (2014)

SMOC can act as both an antagonist and an expander of BMP signaling
por: Thomas, J Terrig, et al.
Publicado: (2017)

The BMP Antagonist Follistatin-Like 1 Is Required for Skeletal and Lung Organogenesis
por: Sylva, Marc, et al.
Publicado: (2011)

Holoprosencephaly with a Special Form of Anophthalmia Result from Experimental Induction of bmp4, Oversaturating BMP Antagonists in Zebrafish
por: Bulk, Johannes, et al.
Publicado: (2023)

Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation
por: Nistala, Harikiran, et al.
Publicado: (2010)

GDF-5 can act as a context-dependent BMP-2 antagonist
por: Klammert, Uwe, et al.
Publicado: (2015)

Calreticulin is a secreted BMP antagonist, expressed in Hensen's node during neural induction
por: De Almeida, Irene, et al.
Publicado: (2017)

Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist
por: van Bezooijen, Rutger L., et al.
Publicado: (2004)

Application of BMP in Bone Tissue Engineering
por: Zhu, Liwei, et al.
Publicado: (2022)

BMP Signaling Pathway in Dentin Development and Diseases
por: Liu, Mengmeng, et al.
Publicado: (2022)

Nobiletin, a NF‐κB signaling antagonist, promotes BMP‐induced bone formation
por: Rojasawasthien, Thira, et al.
Publicado: (2022)

A Secreted BMP Antagonist, Cer1, Fine Tunes the Spatial Organization of the Ureteric Bud Tree during Mouse Kidney Development
por: Chi, Lijun, et al.
Publicado: (2011)

BMP Receptor Inhibition Enhances Tissue Repair in Endoglin Heterozygous Mice
por: Bakker, Wineke, et al.
Publicado: (2021)

Bone Morphogenetic Protein (BMP) signaling in development and human diseases
por: Wang, Richard N., et al.
Publicado: (2014)

Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin
por: Frank, Natasha Y., et al.
Publicado: (2006)

Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice
por: Rainger, Joe, et al.
Publicado: (2011)

Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues
por: Aleman, Abigail, et al.
Publicado: (2014)

Opposing roles and potential antagonistic mechanism between TGF-β and BMP pathways: Implications for cancer progression
por: Ning, Junya, et al.
Publicado: (2019)

BMP8 and activated brown adipose tissue in human newborns
por: Urisarri, Adela, et al.
Publicado: (2021)

BMP-dependent synaptic development requires Abi-Abl-Rac signaling of BMP receptor macropinocytosis
por: Kim, Najin, et al.
Publicado: (2019)

Adipose tissue plasticity and the pleiotropic roles of BMP signaling
por: Qian, Shuwen, et al.
Publicado: (2021)

Sostdc1: A soluble BMP and Wnt antagonist that is induced by the interaction between myeloma cells and osteoblast lineage cells
por: Faraahi, Z., et al.
Publicado: (2019)

Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA
por: Kobielak, Krzysztof, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_mr9u9dig0ipnjhhiqbtt6eqt0f