Effective asymmetric preparation of (R)-1-[3-(trifluoromethyl)phenyl]ethanol with recombinant E. coli whole cells in an aqueous Tween-20/natural deep eutectic solvent solution

(R)-1-[3-(Trifluoromethyl)phenyl]ethanol ((R)-MTF-PEL) is an important chiral building block for the synthesis of a neuroprotective compound, (R)-3-(1-(3-(trifluoromethyl)phenyl)ethoxy)azetidine-1-carboxamide. In this work, an effective whole-cell-catalyzed biotransformation was developed to produce...

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Detalles Bibliográficos
Autores principales: Zhuang, Wenjin, Liu, Hanyu, Zhang, Ying, He, Junyao, Wang, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377109/
https://www.ncbi.nlm.nih.gov/pubmed/34410519
http://dx.doi.org/10.1186/s13568-021-01278-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377109/
https://www.ncbi.nlm.nih.gov/pubmed/34410519
http://dx.doi.org/10.1186/s13568-021-01278-6

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