Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma

Ocular repeated air blast injuries occur from low overpressure blast wave exposure, which are often repeated and in quick succession. We have shown that caspase-2 caused the death of retinal ganglion cells (RGC) after blunt ocular trauma. Here, we investigated if caspase-2 also mediates RGC apoptosi...

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Detalles Bibliográficos
Autores principales: Thomas, Chloe N., Bernardo-Colón, Alexandra, Courtie, Ella, Essex, Gareth, Rex, Tonia S., Blanch, Richard J., Ahmed, Zubair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377143/
https://www.ncbi.nlm.nih.gov/pubmed/34413361
http://dx.doi.org/10.1038/s41598-021-96107-y

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