Gravity-induced loss of aeration and atelectasis development in the preterm lung: a serial sonographic assessment

OBJECTIVE: To assess the impact of gravity and time on the changes in the distribution patterns of loss of aeration and atelectasis development in very preterm infants. STUDY DESIGN: Preterm infants less than 32 weeks gestation were included in this prospective, observational study. Infants were ass...

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Autores principales: Hoshino, Yusuke, Arai, Junichi, Hirono, Koji, Maruo, Kazushi, Kajikawa, Daigo, Yukitake, Yoshiya, Hinata, Ayako, Miura, Rena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377153/
https://www.ncbi.nlm.nih.gov/pubmed/34417561
http://dx.doi.org/10.1038/s41372-021-01189-1
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author Hoshino, Yusuke
Arai, Junichi
Hirono, Koji
Maruo, Kazushi
Kajikawa, Daigo
Yukitake, Yoshiya
Hinata, Ayako
Miura, Rena
author_facet Hoshino, Yusuke
Arai, Junichi
Hirono, Koji
Maruo, Kazushi
Kajikawa, Daigo
Yukitake, Yoshiya
Hinata, Ayako
Miura, Rena
author_sort Hoshino, Yusuke
collection PubMed
description OBJECTIVE: To assess the impact of gravity and time on the changes in the distribution patterns of loss of aeration and atelectasis development in very preterm infants. STUDY DESIGN: Preterm infants less than 32 weeks gestation were included in this prospective, observational study. Infants were assessed via serial lung ultrasound (LUS) score in four lung zones, performed on days 7, 14, 21, and 28 after birth. RESULT: Eighty-eight patients were enrolled. There was a significant main effect of gravity (P < 0.001) and time (P = 0.01) on the LUS score between gravity-dependent lungs and non-dependent lungs. Moreover, there was a significant main effect of gravity (P = 0.003) on atelectasis development between the lungs. CONCLUSION: Gravity and time have an impact on the changes in the distribution patterns of gravity-induced lung injuries in preterm infants.
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spelling pubmed-83771532021-08-20 Gravity-induced loss of aeration and atelectasis development in the preterm lung: a serial sonographic assessment Hoshino, Yusuke Arai, Junichi Hirono, Koji Maruo, Kazushi Kajikawa, Daigo Yukitake, Yoshiya Hinata, Ayako Miura, Rena J Perinatol Article OBJECTIVE: To assess the impact of gravity and time on the changes in the distribution patterns of loss of aeration and atelectasis development in very preterm infants. STUDY DESIGN: Preterm infants less than 32 weeks gestation were included in this prospective, observational study. Infants were assessed via serial lung ultrasound (LUS) score in four lung zones, performed on days 7, 14, 21, and 28 after birth. RESULT: Eighty-eight patients were enrolled. There was a significant main effect of gravity (P < 0.001) and time (P = 0.01) on the LUS score between gravity-dependent lungs and non-dependent lungs. Moreover, there was a significant main effect of gravity (P = 0.003) on atelectasis development between the lungs. CONCLUSION: Gravity and time have an impact on the changes in the distribution patterns of gravity-induced lung injuries in preterm infants. Nature Publishing Group US 2021-08-20 2022 /pmc/articles/PMC8377153/ /pubmed/34417561 http://dx.doi.org/10.1038/s41372-021-01189-1 Text en © The Author(s), under exclusive licence to Springer Nature America, Inc. 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Hoshino, Yusuke
Arai, Junichi
Hirono, Koji
Maruo, Kazushi
Kajikawa, Daigo
Yukitake, Yoshiya
Hinata, Ayako
Miura, Rena
Gravity-induced loss of aeration and atelectasis development in the preterm lung: a serial sonographic assessment
title Gravity-induced loss of aeration and atelectasis development in the preterm lung: a serial sonographic assessment
title_full Gravity-induced loss of aeration and atelectasis development in the preterm lung: a serial sonographic assessment
title_fullStr Gravity-induced loss of aeration and atelectasis development in the preterm lung: a serial sonographic assessment
title_full_unstemmed Gravity-induced loss of aeration and atelectasis development in the preterm lung: a serial sonographic assessment
title_short Gravity-induced loss of aeration and atelectasis development in the preterm lung: a serial sonographic assessment
title_sort gravity-induced loss of aeration and atelectasis development in the preterm lung: a serial sonographic assessment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377153/
https://www.ncbi.nlm.nih.gov/pubmed/34417561
http://dx.doi.org/10.1038/s41372-021-01189-1
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