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Intervention by picroside II on FFAs induced lipid accumulation and lipotoxicity in HepG2 cells

BACKGROUND: Accumulation of free fatty acids (FFAs) in hepatocytes is a hallmark of liver dysfunction and non-alcoholic fatty liver disease (NAFLD). Excessive deposition of FFAs alters lipid metabolism pathways increasing the oxidative stress and mitochondrial dysfunction. Attenuating hepatic lipid...

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Detalles Bibliográficos
Autores principales:	Dhami-Shah, Hiteshi, Vaidya, Rama, Talwadekar, Manasi, Shaw, Eisha, Udipi, Shobha, Kolthur-Seetharam, Ullas, Vaidya, Ashok D.B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research Article (Experimental)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377190/ https://www.ncbi.nlm.nih.gov/pubmed/34353693 http://dx.doi.org/10.1016/j.jaim.2021.04.007

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