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PI3K in T Cell Adhesion and Trafficking

PI3K signalling is required for activation, differentiation, and trafficking of T cells. PI3Kδ, the dominant PI3K isoform in T cells, has been extensively characterised using PI3Kδ mutant mouse models and PI3K inhibitors. Furthermore, characterisation of patients with Activated PI3K Delta Syndrome (...

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Detalles Bibliográficos
Autores principales:	Johansen, Kristoffer H., Golec, Dominic P., Thomsen, Julie H., Schwartzberg, Pamela L., Okkenhaug, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377255/ https://www.ncbi.nlm.nih.gov/pubmed/34421914 http://dx.doi.org/10.3389/fimmu.2021.708908

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