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Gene expression correlates of advanced epigenetic age and psychopathology in postmortem cortical tissue

Psychiatric stress has been associated with accelerated epigenetic aging (i.e., when estimates of cellular age based on DNA methylation exceed chronological age) in both blood and brain tissue. Little is known about the downstream biological effects of accelerated epigenetic age on gene expression....

Fuld beskrivelse

Bibliografiske detaljer
Autores principales: Wolf, Erika J., Zhao, Xiang, Hawn, Sage E., Morrison, Filomene G., Zhou, Zhenwei, Fein-Schaffer, Dana, Huber, Bertrand, Miller, Mark W., Logue, Mark W.
Format: Online Artículo Texto
Sprog:English
Udgivet: Elsevier 2021
Fag:
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377489/
https://www.ncbi.nlm.nih.gov/pubmed/34458511
http://dx.doi.org/10.1016/j.ynstr.2021.100371