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Gene expression correlates of advanced epigenetic age and psychopathology in postmortem cortical tissue

Psychiatric stress has been associated with accelerated epigenetic aging (i.e., when estimates of cellular age based on DNA methylation exceed chronological age) in both blood and brain tissue. Little is known about the downstream biological effects of accelerated epigenetic age on gene expression....

Полное описание

Библиографические подробности
Главные авторы: Wolf, Erika J., Zhao, Xiang, Hawn, Sage E., Morrison, Filomene G., Zhou, Zhenwei, Fein-Schaffer, Dana, Huber, Bertrand, Miller, Mark W., Logue, Mark W.
Формат: Online Статья Текст
Язык:English
Опубликовано: Elsevier 2021
Предметы:
Online-ссылка:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377489/
https://www.ncbi.nlm.nih.gov/pubmed/34458511
http://dx.doi.org/10.1016/j.ynstr.2021.100371