A high-throughput DNA FISH protocol to visualize genome regions in human cells

Here, we describe an end-to-end high-throughput imaging protocol to visualize genomic loci in cells at high throughput using DNA fluorescence in situ hybridization, automated microscopy, and computational analysis. This is particularly useful for quantifying patterns of heterogeneity in relative gen...

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Detalles Bibliográficos
Autores principales: Finn, Elizabeth H., Misteli, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377592/
https://www.ncbi.nlm.nih.gov/pubmed/34458868
http://dx.doi.org/10.1016/j.xpro.2021.100741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377592/
https://www.ncbi.nlm.nih.gov/pubmed/34458868
http://dx.doi.org/10.1016/j.xpro.2021.100741

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