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A high-throughput DNA FISH protocol to visualize genome regions in human cells
Here, we describe an end-to-end high-throughput imaging protocol to visualize genomic loci in cells at high throughput using DNA fluorescence in situ hybridization, automated microscopy, and computational analysis. This is particularly useful for quantifying patterns of heterogeneity in relative gen...
Autores principales: | Finn, Elizabeth H., Misteli, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377592/ https://www.ncbi.nlm.nih.gov/pubmed/34458868 http://dx.doi.org/10.1016/j.xpro.2021.100741 |
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