Cargando…

Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice

Mantle cell lymphoma (MCL) is an aggressive B cell lymphoma with poor long-term overall survival. Currently, MCL research and development of potential cures is hampered by the lack of good in vivo models. MCL is characterized by recurrent translocations of CCND1 or CCND2, resulting in overexpression...

Descripción completa

Detalles Bibliográficos
Autores principales: Pieters, Tim, T’Sas, Sara, Vanhee, Stijn, Almeida, André, Driege, Yasmine, Roels, Juliette, Van Loocke, Wouter, Daneels, Willem, Baens, Mathijs, Marchand, Arnaud, Van Trimpont, Maaike, Matthijssens, Filip, Morscio, Julie, Lemeire, Kelly, Lintermans, Béatrice, Reunes, Lindy, Chaltin, Patrick, Offner, Fritz, Van Dorpe, Jo, Hochepied, Tino, Berx, Geert, Beyaert, Rudi, Staal, Jens, Van Vlierberghe, Pieter, Goossens, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377631/
https://www.ncbi.nlm.nih.gov/pubmed/34406363
http://dx.doi.org/10.1084/jem.20202280