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Uncovering Spatiotemporal Heterogeneity of High-Grade Gliomas: From Disease Biology to Therapeutic Implications

Glioblastomas (GBM) are the most common and aggressive tumors of the central nervous system. Rapid tumor growth and diffuse infiltration into healthy brain tissue, along with high intratumoral heterogeneity, challenge therapeutic efficacy and prognosis. A better understanding of spatiotemporal tumor...

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Detalles Bibliográficos
Autores principales:	Comba, Andrea, Faisal, Syed M., Varela, Maria Luisa, Hollon, Todd, Al-Holou, Wajd N., Umemura, Yoshie, Nunez, Felipe J., Motsch, Sebastien, Castro, Maria G., Lowenstein, Pedro R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377724/ https://www.ncbi.nlm.nih.gov/pubmed/34422657 http://dx.doi.org/10.3389/fonc.2021.703764

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