CB2-mediated attenuation of nucleus pulposus degeneration via the amelioration of inflammation and oxidative stress in vivo and in vitro

BACKGROUND: Nucleus pulposus cell (NPC) degeneration is widely accepted as one of the major causes of intervertebral disc (IVD) degeneration (IVDD). The pathogenesis of IVDD is complex and consists of inflammation, oxidative stress, and the loss of extracellular matrix (ECM). Cannabinoid type 2 rece...

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Detalles Bibliográficos
Autores principales: Cheng, Xiaoqiang, Lin, Jiayi, Chen, Zhanghuan, Mao, Yubo, Wu, Xiexin, Xu, Congxin, Du, Jiacheng, Dong, Zhongchen, Yang, Huilin, Zhou, Feng, Geng, Dechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8377943/
https://www.ncbi.nlm.nih.gov/pubmed/34412587
http://dx.doi.org/10.1186/s10020-021-00351-x

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