Epitope diversity of SARS-CoV-2 hyperimmune intravenous human immunoglobulins and neutralization of variants of concern

Hyperimmune immunoglobulin (hCoV-2IG) generated from SARS-CoV-2 convalescent plasma (CP) are under evaluation in clinical trials. Here we explored the antibody epitope repertoire, and virus neutralizing capacity of six hCoV-2IG batches as well as nine CP against SARS-CoV-2 and emerging variants of c...

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Detalles Bibliográficos
Autores principales: Tang, Juanjie, Lee, Youri, Ravichandran, Supriya, Grubbs, Gabrielle, Huang, Chang, Stauft, Charles B., Wang, Tony, Golding, Basil, Golding, Hana, Khurana, Surender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378063/
https://www.ncbi.nlm.nih.gov/pubmed/34430803
http://dx.doi.org/10.1016/j.isci.2021.103006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378063/
https://www.ncbi.nlm.nih.gov/pubmed/34430803
http://dx.doi.org/10.1016/j.isci.2021.103006

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