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Epitope diversity of SARS-CoV-2 hyperimmune intravenous human immunoglobulins and neutralization of variants of concern

Hyperimmune immunoglobulin (hCoV-2IG) generated from SARS-CoV-2 convalescent plasma (CP) are under evaluation in clinical trials. Here we explored the antibody epitope repertoire, and virus neutralizing capacity of six hCoV-2IG batches as well as nine CP against SARS-CoV-2 and emerging variants of c...

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Detalles Bibliográficos
Autores principales:	Tang, Juanjie, Lee, Youri, Ravichandran, Supriya, Grubbs, Gabrielle, Huang, Chang, Stauft, Charles B., Wang, Tony, Golding, Basil, Golding, Hana, Khurana, Surender
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378063/ https://www.ncbi.nlm.nih.gov/pubmed/34430803 http://dx.doi.org/10.1016/j.isci.2021.103006

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