Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out

The national human immunodeficiency virus (HIV) mother-to-child transmission rate at 6–10 weeks post-partum was 0.9% in 2016. There is a paucity of data about the intrapartum transmission rate after lifelong antiretroviral therapy was implemented in 2015. We assessed all pregnant women living with H...

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Autores principales: van der Merwe, Tian A., van Zyl, Gert U., Lombard, Carl J., Theron, Gerhard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS OpenJournals 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378200/
https://www.ncbi.nlm.nih.gov/pubmed/34485480
http://dx.doi.org/10.4102/sajid.v35i1.192
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author van der Merwe, Tian A.
van Zyl, Gert U.
Lombard, Carl J.
Theron, Gerhard B.
author_facet van der Merwe, Tian A.
van Zyl, Gert U.
Lombard, Carl J.
Theron, Gerhard B.
author_sort van der Merwe, Tian A.
collection PubMed
description The national human immunodeficiency virus (HIV) mother-to-child transmission rate at 6–10 weeks post-partum was 0.9% in 2016. There is a paucity of data about the intrapartum transmission rate after lifelong antiretroviral therapy was implemented in 2015. We assessed all pregnant women living with HIV who delivered at Tygerberg Hospital in 2017. Positive polymerase chain reactions (PCRs) at birth indicated an in utero transmission rate of 0.8%. One infant with a negative PCR at birth tested positive at 6–10 weeks. The intrapartum transmission rate was low (0.08%). About 25% of infants were lost to follow-up after birth.
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spelling pubmed-83782002021-09-03 Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out van der Merwe, Tian A. van Zyl, Gert U. Lombard, Carl J. Theron, Gerhard B. S Afr J Infect Dis Brief Report The national human immunodeficiency virus (HIV) mother-to-child transmission rate at 6–10 weeks post-partum was 0.9% in 2016. There is a paucity of data about the intrapartum transmission rate after lifelong antiretroviral therapy was implemented in 2015. We assessed all pregnant women living with HIV who delivered at Tygerberg Hospital in 2017. Positive polymerase chain reactions (PCRs) at birth indicated an in utero transmission rate of 0.8%. One infant with a negative PCR at birth tested positive at 6–10 weeks. The intrapartum transmission rate was low (0.08%). About 25% of infants were lost to follow-up after birth. AOSIS OpenJournals 2020-12-03 /pmc/articles/PMC8378200/ /pubmed/34485480 http://dx.doi.org/10.4102/sajid.v35i1.192 Text en © 2020. The Authors https://creativecommons.org/licenses/by/4.0/Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.
spellingShingle Brief Report
van der Merwe, Tian A.
van Zyl, Gert U.
Lombard, Carl J.
Theron, Gerhard B.
Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out
title Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out
title_full Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out
title_fullStr Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out
title_full_unstemmed Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out
title_short Intrapartum human immunodeficiency virus transmission rate in a central hospital in the Western Cape province after universal antiretroviral therapy roll-out
title_sort intrapartum human immunodeficiency virus transmission rate in a central hospital in the western cape province after universal antiretroviral therapy roll-out
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378200/
https://www.ncbi.nlm.nih.gov/pubmed/34485480
http://dx.doi.org/10.4102/sajid.v35i1.192
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