Fibril Surface-Dependent Amyloid Precursors Revealed by Coarse-Grained Molecular Dynamics Simulation

Amyloid peptides are known to self-assemble into larger aggregates that are linked to the pathogenesis of many neurodegenerative disorders. In contrast to primary nucleation, recent experimental and theoretical studies have shown that many toxic oligomeric species are generated through secondary pro...

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Detalles Bibliográficos
Autores principales: Ma, Yuan-Wei, Lin, Tong-You, Tsai, Min-Yeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378332/
https://www.ncbi.nlm.nih.gov/pubmed/34422910
http://dx.doi.org/10.3389/fmolb.2021.719320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378332/
https://www.ncbi.nlm.nih.gov/pubmed/34422910
http://dx.doi.org/10.3389/fmolb.2021.719320

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