Cargando…
Molecular and pharmacological characterization of insulin icodec: a new basal insulin analog designed for once-weekly dosing
INTRODUCTION: Insulin icodec is a novel, long-acting insulin analog designed to cover basal insulin requirements with once-weekly subcutaneous administration. Here we describe the molecular engineering and the biological and pharmacological properties of insulin icodec. RESEARCH DESIGN AND METHODS:...
Autores principales: | Nishimura, Erica, Pridal, Lone, Glendorf, Tine, Hansen, Bo Falk, Hubálek, František, Kjeldsen, Thomas, Kristensen, Niels Rode, Lützen, Anne, Lyby, Karsten, Madsen, Peter, Pedersen, Thomas Åskov, Ribel-Madsen, Rasmus, Stidsen, Carsten Enggaard, Haahr, Hanne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378355/ https://www.ncbi.nlm.nih.gov/pubmed/34413118 http://dx.doi.org/10.1136/bmjdrc-2021-002301 |
Ejemplares similares
-
Molecular Characterisation of Long-Acting Insulin Analogues in Comparison with Human Insulin, IGF-1 and Insulin X10
por: Hansen, Bo F., et al.
Publicado: (2012) -
Engineering of Insulin Receptor Isoform-Selective Insulin Analogues
por: Glendorf, Tine, et al.
Publicado: (2011) -
Molecular engineering of safe and efficacious oral basal insulin
por: Hubálek, Frantisek, et al.
Publicado: (2020) -
Author Correction: Molecular engineering of safe and efficacious
oral basal insulin
por: Hubálek, Frantisek, et al.
Publicado: (2020) -
Hypoglycaemia frequency and physiological response after double or triple doses of once-weekly insulin icodec vs once-daily insulin glargine U100 in type 2 diabetes: a randomised crossover trial
por: Pieber, Thomas R., et al.
Publicado: (2023)