Cargando…
The Relation of ABO Blood Group to the Severity of Coronavirus Disease: A Cross-Sectional Study From a Tertiary Care Hospital in Karachi
Background Blood groups are considered to have an impact on the occurrence and severity of coronavirus disease. While among Chinese and Caucasian, blood group O individuals were less and group A were more likely to have severe disease and mortality, data on South Asians aren’t available. Objective...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378412/ https://www.ncbi.nlm.nih.gov/pubmed/34430180 http://dx.doi.org/10.7759/cureus.16598 |
_version_ | 1783740829457711104 |
---|---|
author | Rehman, Fazal U Omair, Syed Furrukh Memon, Fatima Rind, Bakhtawar J Memon, Danish Ahmed Ali, Syed Ahsan Ahmed, Bilal Ali, Naureen |
author_facet | Rehman, Fazal U Omair, Syed Furrukh Memon, Fatima Rind, Bakhtawar J Memon, Danish Ahmed Ali, Syed Ahsan Ahmed, Bilal Ali, Naureen |
author_sort | Rehman, Fazal U |
collection | PubMed |
description | Background Blood groups are considered to have an impact on the occurrence and severity of coronavirus disease. While among Chinese and Caucasian, blood group O individuals were less and group A were more likely to have severe disease and mortality, data on South Asians aren’t available. Objective This study aimed to find out the association of disease severity with blood group among coronavirus disease 2019 (COVID-19) patients. Materials and methodology Data were collected on a predesigned questionnaire containing details of patient demographics, medical comorbidities, clinical presentation, and laboratory parameters. Multiple logistic regression was used to determine the association of the blood group with the severity of coronavirus disease. Result Among the study participants, blood group B has the highest distribution (39.8%), followed by O (30.0), A (21.9%), and AB (8.1%). About three-fourths (69.9%) had mild to moderate disease while 30.0% had severe disease. Age, gender, hypertension, diabetes mellitus, and hemoglobin level were all associated with disease severity among COVID-19 patients in univariate analysis on P-value for selection (<0.25). The final model showed that the odds of disease severity is 3.62 times higher among males (OR: 3.62, 95% CI: 2.15-6.08) and 2.00 times higher among diabetic patients (OR: 2.00, 95% CI: 1.10-3.01) as compared to female and non-diabetic respectively. However, there was no significant association found between blood group and disease severity. Conclusion Blood groups don’t have any role in forecasting the severity of coronavirus disease. However, the male gender and diabetics are prone to have severe disease. |
format | Online Article Text |
id | pubmed-8378412 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-83784122021-08-23 The Relation of ABO Blood Group to the Severity of Coronavirus Disease: A Cross-Sectional Study From a Tertiary Care Hospital in Karachi Rehman, Fazal U Omair, Syed Furrukh Memon, Fatima Rind, Bakhtawar J Memon, Danish Ahmed Ali, Syed Ahsan Ahmed, Bilal Ali, Naureen Cureus Infectious Disease Background Blood groups are considered to have an impact on the occurrence and severity of coronavirus disease. While among Chinese and Caucasian, blood group O individuals were less and group A were more likely to have severe disease and mortality, data on South Asians aren’t available. Objective This study aimed to find out the association of disease severity with blood group among coronavirus disease 2019 (COVID-19) patients. Materials and methodology Data were collected on a predesigned questionnaire containing details of patient demographics, medical comorbidities, clinical presentation, and laboratory parameters. Multiple logistic regression was used to determine the association of the blood group with the severity of coronavirus disease. Result Among the study participants, blood group B has the highest distribution (39.8%), followed by O (30.0), A (21.9%), and AB (8.1%). About three-fourths (69.9%) had mild to moderate disease while 30.0% had severe disease. Age, gender, hypertension, diabetes mellitus, and hemoglobin level were all associated with disease severity among COVID-19 patients in univariate analysis on P-value for selection (<0.25). The final model showed that the odds of disease severity is 3.62 times higher among males (OR: 3.62, 95% CI: 2.15-6.08) and 2.00 times higher among diabetic patients (OR: 2.00, 95% CI: 1.10-3.01) as compared to female and non-diabetic respectively. However, there was no significant association found between blood group and disease severity. Conclusion Blood groups don’t have any role in forecasting the severity of coronavirus disease. However, the male gender and diabetics are prone to have severe disease. Cureus 2021-07-23 /pmc/articles/PMC8378412/ /pubmed/34430180 http://dx.doi.org/10.7759/cureus.16598 Text en Copyright © 2021, Rehman et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Infectious Disease Rehman, Fazal U Omair, Syed Furrukh Memon, Fatima Rind, Bakhtawar J Memon, Danish Ahmed Ali, Syed Ahsan Ahmed, Bilal Ali, Naureen The Relation of ABO Blood Group to the Severity of Coronavirus Disease: A Cross-Sectional Study From a Tertiary Care Hospital in Karachi |
title | The Relation of ABO Blood Group to the Severity of Coronavirus Disease: A Cross-Sectional Study From a Tertiary Care Hospital in Karachi |
title_full | The Relation of ABO Blood Group to the Severity of Coronavirus Disease: A Cross-Sectional Study From a Tertiary Care Hospital in Karachi |
title_fullStr | The Relation of ABO Blood Group to the Severity of Coronavirus Disease: A Cross-Sectional Study From a Tertiary Care Hospital in Karachi |
title_full_unstemmed | The Relation of ABO Blood Group to the Severity of Coronavirus Disease: A Cross-Sectional Study From a Tertiary Care Hospital in Karachi |
title_short | The Relation of ABO Blood Group to the Severity of Coronavirus Disease: A Cross-Sectional Study From a Tertiary Care Hospital in Karachi |
title_sort | relation of abo blood group to the severity of coronavirus disease: a cross-sectional study from a tertiary care hospital in karachi |
topic | Infectious Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378412/ https://www.ncbi.nlm.nih.gov/pubmed/34430180 http://dx.doi.org/10.7759/cureus.16598 |
work_keys_str_mv | AT rehmanfazalu therelationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT omairsyedfurrukh therelationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT memonfatima therelationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT rindbakhtawarj therelationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT memondanishahmed therelationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT alisyedahsan therelationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT ahmedbilal therelationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT alinaureen therelationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT rehmanfazalu relationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT omairsyedfurrukh relationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT memonfatima relationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT rindbakhtawarj relationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT memondanishahmed relationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT alisyedahsan relationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT ahmedbilal relationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi AT alinaureen relationofabobloodgrouptotheseverityofcoronavirusdiseaseacrosssectionalstudyfromatertiarycarehospitalinkarachi |