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Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver

Ultradian glucocorticoid rhythms are highly conserved across mammalian species, however, their functional significance is not yet fully understood. Here we demonstrate that pulsatile corticosterone replacement in adrenalectomised rats induces a dynamic pattern of glucocorticoid receptor (GR) binding...

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Detalles Bibliográficos
Autores principales:	Flynn, Benjamin P., Birnie, Matthew T., Kershaw, Yvonne M., Pauza, Audrys G., Kim, Sohyoung, Baek, Songjoon, Rogers, Mark F., Paterson, Alex R., Stavreva, Diana A., Murphy, David, Hager, Gordon L., Lightman, Stafford L., Conway-Campbell, Becky L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378686/ https://www.ncbi.nlm.nih.gov/pubmed/34375333 http://dx.doi.org/10.1371/journal.pgen.1009737

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