Single-chain Fragment variable antibody targeting cholecystokinin-B receptor for pain reduction

The cholecystokinin B receptor and its neuropeptide ligand are upregulated in chronic neuropathic pain models. Single-chain Fragment variable antibodies were generated as preferred non-opioid targeting therapy blocking the cholecystokinin B receptor to inhibit chronic neuropathic pain models in vivo...

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Detalles Bibliográficos
Autores principales: Westlund, K.N., Montera, M.A., Goins, A.E., Alles, S.R.A., Afaghpour-Becklund, M., Bartel, R., Durvasula, R., Kunamneni, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378781/
https://www.ncbi.nlm.nih.gov/pubmed/34458647
http://dx.doi.org/10.1016/j.ynpai.2021.100067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378781/
https://www.ncbi.nlm.nih.gov/pubmed/34458647
http://dx.doi.org/10.1016/j.ynpai.2021.100067

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