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Single-chain Fragment variable antibody targeting cholecystokinin-B receptor for pain reduction
The cholecystokinin B receptor and its neuropeptide ligand are upregulated in chronic neuropathic pain models. Single-chain Fragment variable antibodies were generated as preferred non-opioid targeting therapy blocking the cholecystokinin B receptor to inhibit chronic neuropathic pain models in vivo...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378781/ https://www.ncbi.nlm.nih.gov/pubmed/34458647 http://dx.doi.org/10.1016/j.ynpai.2021.100067 |