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Multi-task driven explainable diagnosis of COVID-19 using chest X-ray images

With increasing number of COVID-19 cases globally, all the countries are ramping up the testing numbers. While the RT-PCR kits are available in sufficient quantity in several countries, others are facing challenges with limited availability of testing kits and processing centers in remote areas. Thi...

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Autores principales: Malhotra, Aakarsh, Mittal, Surbhi, Majumdar, Puspita, Chhabra, Saheb, Thakral, Kartik, Vatsa, Mayank, Singh, Richa, Chaudhury, Santanu, Pudrod, Ashwin, Agrawal, Anjali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379001/
https://www.ncbi.nlm.nih.gov/pubmed/34456368
http://dx.doi.org/10.1016/j.patcog.2021.108243
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author Malhotra, Aakarsh
Mittal, Surbhi
Majumdar, Puspita
Chhabra, Saheb
Thakral, Kartik
Vatsa, Mayank
Singh, Richa
Chaudhury, Santanu
Pudrod, Ashwin
Agrawal, Anjali
author_facet Malhotra, Aakarsh
Mittal, Surbhi
Majumdar, Puspita
Chhabra, Saheb
Thakral, Kartik
Vatsa, Mayank
Singh, Richa
Chaudhury, Santanu
Pudrod, Ashwin
Agrawal, Anjali
author_sort Malhotra, Aakarsh
collection PubMed
description With increasing number of COVID-19 cases globally, all the countries are ramping up the testing numbers. While the RT-PCR kits are available in sufficient quantity in several countries, others are facing challenges with limited availability of testing kits and processing centers in remote areas. This has motivated researchers to find alternate methods of testing which are reliable, easily accessible and faster. Chest X-Ray is one of the modalities that is gaining acceptance as a screening modality. Towards this direction, the paper has two primary contributions. Firstly, we present the COVID-19 Multi-Task Network (COMiT-Net) which is an automated end-to-end network for COVID-19 screening. The proposed network not only predicts whether the CXR has COVID-19 features present or not, it also performs semantic segmentation of the regions of interest to make the model explainable. Secondly, with the help of medical professionals, we manually annotate the lung regions and semantic segmentation of COVID19 symptoms in CXRs taken from the ChestXray-14, CheXpert, and a consolidated COVID-19 dataset. These annotations will be released to the research community. Experiments performed with more than 2500 frontal CXR images show that at 90% specificity, the proposed COMiT-Net yields 96.80% sensitivity.
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spelling pubmed-83790012021-08-23 Multi-task driven explainable diagnosis of COVID-19 using chest X-ray images Malhotra, Aakarsh Mittal, Surbhi Majumdar, Puspita Chhabra, Saheb Thakral, Kartik Vatsa, Mayank Singh, Richa Chaudhury, Santanu Pudrod, Ashwin Agrawal, Anjali Pattern Recognit Article With increasing number of COVID-19 cases globally, all the countries are ramping up the testing numbers. While the RT-PCR kits are available in sufficient quantity in several countries, others are facing challenges with limited availability of testing kits and processing centers in remote areas. This has motivated researchers to find alternate methods of testing which are reliable, easily accessible and faster. Chest X-Ray is one of the modalities that is gaining acceptance as a screening modality. Towards this direction, the paper has two primary contributions. Firstly, we present the COVID-19 Multi-Task Network (COMiT-Net) which is an automated end-to-end network for COVID-19 screening. The proposed network not only predicts whether the CXR has COVID-19 features present or not, it also performs semantic segmentation of the regions of interest to make the model explainable. Secondly, with the help of medical professionals, we manually annotate the lung regions and semantic segmentation of COVID19 symptoms in CXRs taken from the ChestXray-14, CheXpert, and a consolidated COVID-19 dataset. These annotations will be released to the research community. Experiments performed with more than 2500 frontal CXR images show that at 90% specificity, the proposed COMiT-Net yields 96.80% sensitivity. Published by Elsevier Ltd. 2022-02 2021-08-21 /pmc/articles/PMC8379001/ /pubmed/34456368 http://dx.doi.org/10.1016/j.patcog.2021.108243 Text en © 2021 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Malhotra, Aakarsh
Mittal, Surbhi
Majumdar, Puspita
Chhabra, Saheb
Thakral, Kartik
Vatsa, Mayank
Singh, Richa
Chaudhury, Santanu
Pudrod, Ashwin
Agrawal, Anjali
Multi-task driven explainable diagnosis of COVID-19 using chest X-ray images
title Multi-task driven explainable diagnosis of COVID-19 using chest X-ray images
title_full Multi-task driven explainable diagnosis of COVID-19 using chest X-ray images
title_fullStr Multi-task driven explainable diagnosis of COVID-19 using chest X-ray images
title_full_unstemmed Multi-task driven explainable diagnosis of COVID-19 using chest X-ray images
title_short Multi-task driven explainable diagnosis of COVID-19 using chest X-ray images
title_sort multi-task driven explainable diagnosis of covid-19 using chest x-ray images
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379001/
https://www.ncbi.nlm.nih.gov/pubmed/34456368
http://dx.doi.org/10.1016/j.patcog.2021.108243
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