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Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19

The human immunity has a pivotal role in nutrition acquisition from the pathogens and damaged body tissue during the SARS-CoV-2 virus infection, which may lead to transient overnutrition in the patients, lead to lipotoxicity and further damage in non-adipose tissues, and cause hyperinflammation and...

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Detalles Bibliográficos
Autores principales: Yu, Boxuan, Yu, Ligen, Klionsky, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379086/
https://www.ncbi.nlm.nih.gov/pubmed/34467856
http://dx.doi.org/10.1016/j.mehy.2021.110668
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author Yu, Boxuan
Yu, Ligen
Klionsky, Daniel J.
author_facet Yu, Boxuan
Yu, Ligen
Klionsky, Daniel J.
author_sort Yu, Boxuan
collection PubMed
description The human immunity has a pivotal role in nutrition acquisition from the pathogens and damaged body tissue during the SARS-CoV-2 virus infection, which may lead to transient overnutrition in the patients, lead to lipotoxicity and further damage in non-adipose tissues, and cause hyperinflammation and cytokine storm in severe cases of COVID-19. In view of this, high-quality clinical trials on restrictive eating should be designed to investigate the possible benefits of food intake restriction on patients' recovery from COVID-19 disease.
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spelling pubmed-83790862021-08-23 Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19 Yu, Boxuan Yu, Ligen Klionsky, Daniel J. Med Hypotheses Letter to Editors The human immunity has a pivotal role in nutrition acquisition from the pathogens and damaged body tissue during the SARS-CoV-2 virus infection, which may lead to transient overnutrition in the patients, lead to lipotoxicity and further damage in non-adipose tissues, and cause hyperinflammation and cytokine storm in severe cases of COVID-19. In view of this, high-quality clinical trials on restrictive eating should be designed to investigate the possible benefits of food intake restriction on patients' recovery from COVID-19 disease. Elsevier Ltd. 2021-10 2021-08-21 /pmc/articles/PMC8379086/ /pubmed/34467856 http://dx.doi.org/10.1016/j.mehy.2021.110668 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Letter to Editors
Yu, Boxuan
Yu, Ligen
Klionsky, Daniel J.
Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19
title Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19
title_full Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19
title_fullStr Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19
title_full_unstemmed Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19
title_short Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19
title_sort nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of covid-19
topic Letter to Editors
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379086/
https://www.ncbi.nlm.nih.gov/pubmed/34467856
http://dx.doi.org/10.1016/j.mehy.2021.110668
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