Cargando…
The neutralization potency of anti-SARS-CoV-2 therapeutic human monoclonal antibodies is retained against viral variants
A wide range of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing monoclonal antibodies (mAbs) have been reported, most of which target the spike glycoprotein. Therapeutic implementation of these antibodies has been challenged by emerging SARS-CoV-2 variants harboring mutated...
Autores principales: | Makdasi, Efi, Zvi, Anat, Alcalay, Ron, Noy-Porat, Tal, Peretz, Eldar, Mechaly, Adva, Levy, Yinon, Epstein, Eyal, Chitlaru, Theodor, Tennenhouse, Ariel, Aftalion, Moshe, Gur, David, Paran, Nir, Tamir, Hadas, Zimhony, Oren, Weiss, Shay, Mandelboim, Michal, Mendelson, Ella, Zuckerman, Neta, Nemet, Ital, Kliker, Limor, Yitzhaki, Shmuel, Shapira, Shmuel C., Israely, Tomer, Fleishman, Sarel J., Mazor, Ohad, Rosenfeld, Ronit |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s).
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379094/ https://www.ncbi.nlm.nih.gov/pubmed/34464610 http://dx.doi.org/10.1016/j.celrep.2021.109679 |
Ejemplares similares
-
A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
por: Noy-Porat, Tal, et al.
Publicado: (2020) -
Characterization of antibody-antigen interactions using biolayer interferometry
por: Noy-Porat, Tal, et al.
Publicado: (2021) -
Immunodominant Linear B-Cell Epitopes of SARS-CoV-2 Spike, Identified by Sera from K18-hACE2 Mice Infected with the WT or Variant Viruses
por: Levy, Yinon, et al.
Publicado: (2022) -
Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody
por: Rosenfeld, Ronit, et al.
Publicado: (2021) -
Neutralizing Monoclonal Anti-SARS-CoV-2 Antibodies Isolated from Immunized Rabbits Define Novel Vulnerable Spike-Protein Epitope
por: Makdasi, Efi, et al.
Publicado: (2021)