Cargando…

Target identification of hepatic fibrosis using Pien Tze Huang based on mRNA and lncRNA

Hepatic fibrosis is a spontaneous wound-healing response triggered by chronic liver injury. Pien Tze Huang (PZH), a traditional Chinese herbal medicine, has been widely used to treat various hepatic diseases in Asia. We used a CCl(4)-induced mouse model to establish a PZH group of hepatic fibrosis m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Jinhang, Zhang, Di, Wang, Ting, Chen, Zhiliang, Chen, Luan, Wu, Hao, Huai, Cong, Sun, Jing, Zhang, Na, Wei, Muyun, Hong, Fei, Qin, Shengying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379174/ https://www.ncbi.nlm.nih.gov/pubmed/34417500 http://dx.doi.org/10.1038/s41598-021-96459-5

Ejemplares similares

Identification of circular RNA biomarkers for Pien Tze Huang treatment of CCl(4)-induced liver fibrosis using RNA-sequencing
por: Wang, Ting, et al.
Publicado: (2022)

Therapeutic Potential of Pien Tze Huang on Experimental Autoimmune Encephalomyelitis Rat
por: Qiu, Xuemei, et al.
Publicado: (2018)

Pien Tze Huang alleviate the joint inflammation in collagen-induced arthritis mice
por: Deng, YongQi, et al.
Publicado: (2020)

Pien Tze Huang regulates phosphorylation of metabolic enzymes in mice of hepatocellular carcinoma
por: Lin, Jinxia, et al.
Publicado: (2023)

Evaluation and mechanism study of Pien Tze Huang against EV-A71 infection
por: Wang, Huiqiang, et al.
Publicado: (2023)

Deciphering Antitumor Mechanism of Pien Tze Huang in Mice of Hepatocellular Carcinoma Based on Proteomics
por: Fan, Dancai, et al.
Publicado: (2020)

Quantitative Profiling of Oxylipin Reveals the Mechanism of Pien-Tze-Huang on Alcoholic Liver Disease
por: Zhu, Ziye, et al.
Publicado: (2021)

Therapeutic Potential of Pien-Tze-Huang: A Review on Its Chemical Composition, Pharmacology, and Clinical Application
por: Huang, Lili, et al.
Publicado: (2019)

Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke
por: Zhang, Lihong, et al.
Publicado: (2010)

Pien Tze Huang (PZH) as a Multifunction Medicinal Agent in Traditional Chinese Medicine (TCM): a review on cellular, molecular and physiological mechanisms
por: Chen, Zhiliang
Publicado: (2021)

Inhibition of ovarian cancer cell proliferation by Pien Tze Huang via the AKT-mTOR pathway
por: HE, FAN, et al.
Publicado: (2014)

Uncovering the Mechanism of the Effects of Pien-Tze-Huang on Liver Cancer Using Network Pharmacology and Molecular Docking
por: Liu, Shanghui, et al.
Publicado: (2020)

Pien Tze Huang Gan Bao ameliorates carbon tetrachloride-induced hepatic injury, oxidative stress and inflammation in rats
por: Zhao, Jinyan, et al.
Publicado: (2017)

Pien Tze Huang Inhibits Hypoxia-Induced Angiogenesis via HIF-1α/VEGF-A Pathway in Colorectal Cancer
por: Chen, Hongwei, et al.
Publicado: (2015)

Methanolic Extract of Pien Tze Huang Induces Apoptosis Signaling in Human Osteosarcoma MG63 Cells via Multiple Pathways
por: Fu, Yong, et al.
Publicado: (2016)

Skin rash caused by EGFR-TKI could be treated successfully by Pien Tze Huang Unguentum Compositum: a case report
por: Zhang, Mingzi, et al.
Publicado: (2022)

Pien Tze Huang Alleviates Relapsing-Remitting Experimental Autoimmune Encephalomyelitis Mice by Regulating Th1 and Th17 Cells
por: Qiu, Xuemei, et al.
Publicado: (2018)

Pien-Tze-Huang alleviates CCl(4)-induced liver fibrosis through the inhibition of HSC autophagy and the TGF-β1/Smad2 pathway
por: Zhang, Yuqin, et al.
Publicado: (2022)

Pien Tze Huang inhibits hypoxia-induced epithelial-mesenchymal transition in human colon carcinoma cells through suppression of the HIF-1 pathway
por: CHEN, HONGWEI, et al.
Publicado: (2014)

Pien Tze Huang Overcomes Multidrug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells via Suppression of TGF-β Pathway
por: Shen, Aling, et al.
Publicado: (2014)

Pien-Tze-Huang attenuates neuroinflammation in cerebral ischaemia-reperfusion injury in rats through the TLR4/NF-κB/MAPK pathway
por: Zhang, Xiaoqin, et al.
Publicado: (2021)

Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis
por: Yan, Xiangying, et al.
Publicado: (2023)

Pien Tze Huang induces apoptosis and inhibits proliferation of 5-fluorouracil-resistant colorectal carcinoma cells via increasing miR-22 expression
por: Chen, Zhaorong, et al.
Publicado: (2017)

Pien Tze Huang Gan Bao attenuates carbon tetrachloride-induced hepatocyte apoptosis in rats, associated with suppression of p53 activation and oxidative stress
por: Zhao, Jinyan, et al.
Publicado: (2017)

Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway
por: Liu, Ying, et al.
Publicado: (2023)

ANRIL promotes the regulation of colorectal cancer on lymphatic endothelial cells via VEGF-C and is the key target for Pien Tze Huang to inhibit cancer metastasis
por: Huang, Bin, et al.
Publicado: (2023)

Traditional Chinese Medicine Pien-Tze-Huang Inhibits Colorectal Cancer Growth and Immune Evasion by Reducing β-catenin Transcriptional Activity and PD-L1 Expression
por: Chen, Qiang, et al.
Publicado: (2022)

Case report: Treatment with Pien-Tze-Huang for prolonged positive SARS-CoV-2 test results in COVID-19 patients: A report of five cases
por: Zheng, Yujiao, et al.
Publicado: (2022)

Crosstalk of mRNA, miRNA, lncRNA, and circRNA and Their Regulatory Pattern in Pulmonary Fibrosis
por: Li, Changye, et al.
Publicado: (2019)

Transcriptome sequencing and lncRNA-miRNA-mRNA network construction in cardiac fibrosis and heart failure
por: Wang, Shuo, et al.
Publicado: (2022)

Construction of lncRNA‐miRNA‐mRNA network based on ceRNA mechanism reveals the function of lncRNA in the pathogenesis of gout
por: Chen, Feng, et al.
Publicado: (2022)

Analysis of mRNA‑lncRNA and mRNA‑lncRNA-pathway co‑expression networks based on WGCNA in developing pediatric sepsis
por: Zhang, Xiaojuan, et al.
Publicado: (2021)

The roles of lncRNA in hepatic fibrosis
por: Peng, Hu, et al.
Publicado: (2018)

An Integrated Analysis of miRNA, lncRNA, and mRNA Expression Profiles
por: Guo, Li, et al.
Publicado: (2014)

Identification of cancer-related miRNA-lncRNA biomarkers using a basic miRNA-lncRNA network
por: Zhang, Guangle, et al.
Publicado: (2018)

Integrated analysis of lncRNA and mRNA transcriptomes reveals the potential regulatory role of lncRNA in kiwifruit ripening and softening
por: Chen, Yiting, et al.
Publicado: (2021)

Analysing the relationship between lncRNA and protein-coding gene and the role of lncRNA as ceRNA in pulmonary fibrosis
por: Song, Xiaodong, et al.
Publicado: (2014)

Analysis of PANoptosis-Related LncRNA-miRNA-mRNA Network Reveals LncRNA SNHG7 Involved in Chemo-Resistance in Colon Adenocarcinoma
por: Huang, Jingjing, et al.
Publicado: (2022)

Integrated Dissection of lncRNA-miRNA-mRNA Pairs and Potential Regulatory Role of lncRNA PCAT19 in Lung Adenocarcinoma
por: Tang, Xiaomei, et al.
Publicado: (2022)

Integrated analysis of lncRNA, miRNA and mRNA profiles reveals potential lncRNA functions during early HIV infection
por: Ma, Lianwei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_41if5h9b53qei4agevmm69r8sq