Cargando…

The retinoid X receptor α modulator K-80003 suppresses inflammatory and catabolic responses in a rat model of osteoarthritis

Osteoarthritis (OA), a most common and highly prevalent joint disease, is closely associated with dysregulated expression and modification of RXRα. However, the role of RXRα in the pathophysiology of OA remains unknown. The present study aimed to investigate whether RXRα modulator, such as K-80003 c...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hua, Li, Xiaofan, Yang, Boyu, Su, Junnan, Cai, Shaofang, Huang, Jinmei, Hu, Tianfu, Chen, Lijuan, Xu, Yaping, Li, Yuhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379249/
https://www.ncbi.nlm.nih.gov/pubmed/34417523
http://dx.doi.org/10.1038/s41598-021-96517-y