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The retinoid X receptor α modulator K-80003 suppresses inflammatory and catabolic responses in a rat model of osteoarthritis
Osteoarthritis (OA), a most common and highly prevalent joint disease, is closely associated with dysregulated expression and modification of RXRα. However, the role of RXRα in the pathophysiology of OA remains unknown. The present study aimed to investigate whether RXRα modulator, such as K-80003 c...
Autores principales: | Li, Hua, Li, Xiaofan, Yang, Boyu, Su, Junnan, Cai, Shaofang, Huang, Jinmei, Hu, Tianfu, Chen, Lijuan, Xu, Yaping, Li, Yuhang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379249/ https://www.ncbi.nlm.nih.gov/pubmed/34417523 http://dx.doi.org/10.1038/s41598-021-96517-y |
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