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Saturated very long chain fatty acid configures glycosphingolipid for lysosome homeostasis in long-lived C. elegans

The contents of numerous membrane lipids change upon ageing. However, it is unknown whether and how any of these changes are causally linked to lifespan regulation. Acyl chains contribute to the functional specificity of membrane lipids. In this study, working with C. elegans, we identified an acyl...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Dai, Yuxi, Zhu, Xufeng, Chen, Qilong, Zhu, Huanhu, Zhou, Ben, Tang, Haiqing, Pang, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379269/
https://www.ncbi.nlm.nih.gov/pubmed/34417467
http://dx.doi.org/10.1038/s41467-021-25398-6