Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes

Histone lysine methylations have primarily been linked to selective recruitment of reader or effector proteins that subsequently modify chromatin regions and mediate genome functions. Here, we describe a divergent role for histone H4 lysine 20 mono-methylation (H4K20me1) and demonstrate that it dire...

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Detalles Bibliográficos
Autores principales: Shoaib, Muhammad, Chen, Qinming, Shi, Xiangyan, Nair, Nidhi, Prasanna, Chinmayi, Yang, Renliang, Walter, David, Frederiksen, Klaus S., Einarsson, Hjorleifur, Svensson, J. Peter, Liu, Chuan Fa, Ekwall, Karl, Lerdrup, Mads, Nordenskiöld, Lars, Sørensen, Claus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379281/
https://www.ncbi.nlm.nih.gov/pubmed/34417450
http://dx.doi.org/10.1038/s41467-021-25051-2

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