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Structures of heat shock factor trimers bound to DNA

Heat shock factor 1 (HSF1) and 2 (HSF2) play distinct but overlapping regulatory roles in maintaining cellular proteostasis or mediating cell differentiation and development. Upon activation, both HSFs trimerize and bind to heat shock elements (HSEs) present in the promoter region of target genes. D...

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Detalles Bibliográficos
Autores principales:	Feng, Na, Feng, Han, Wang, Sheng, Punekar, Avinash S., Ladenstein, Rudolf, Wang, Da-Cheng, Zhang, Qinghua, Ding, Jingjin, Liu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379338/ https://www.ncbi.nlm.nih.gov/pubmed/34458700 http://dx.doi.org/10.1016/j.isci.2021.102951

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