Free radical induced activity of an anthracycline analogue and its Mn(II) complex on biological targets through in situ electrochemical generation of semiquinone

Cytotoxicity by anthracycline antibiotics is attributed to several pathways. Important among them are formation of free-radical intermediates. However, their generation makes anthracyclines cardiotoxic which is a concern on their use as anticancer agents. Hence, any change in redox behavior that add...

Descripción completa

Detalles Bibliográficos
Autores principales: Saha, Mouli, Das, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379465/
https://www.ncbi.nlm.nih.gov/pubmed/34458604
http://dx.doi.org/10.1016/j.heliyon.2021.e07746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379465/
https://www.ncbi.nlm.nih.gov/pubmed/34458604
http://dx.doi.org/10.1016/j.heliyon.2021.e07746

Ejemplares similares