The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond–Blackfan anemia by targeting Nemo-like kinase

Nemo-like kinase (NLK) is a member of the mitogen-activated protein kinase family of kinases and shares a highly conserved kinase domain with other mitogen-activated protein kinase family members. The activation of NLK contributes to the pathogenesis of Diamond–Blackfan anemia (DBA), reducing c-myb...

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Detalles Bibliográficos
Autores principales: Wilkes, Mark C., Jung, Kevin, Lee, Britney E., Saxena, Mallika, Sathianathen, Ryan S., Mercado, Jacqueline D., Perez, Cristina, Flygare, Johan, Narla, Anupama, Glader, Bertil, Sakamoto, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379498/
https://www.ncbi.nlm.nih.gov/pubmed/34298020
http://dx.doi.org/10.1016/j.jbc.2021.100988

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