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Semicoordinated allelic-bursting shape dynamic random monoallelic expression in pregastrulation embryos

Recently, allele-specific single-cell RNA-seq analysis has demonstrated widespread dynamic random monoallelic expression of autosomal genes (aRME) in different cell types. However, the prevalence of dynamic aRME during pregastrulation remains unknown. Here, we show that dynamic aRME is widespread in...

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Detalles Bibliográficos
Autores principales: Naik, Hemant Chandru, Hari, Kishore, Chandel, Deepshikha, Mandal, Susmita, Jolly, Mohit Kumar, Gayen, Srimonta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379509/
https://www.ncbi.nlm.nih.gov/pubmed/34458702
http://dx.doi.org/10.1016/j.isci.2021.102954

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