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Semicoordinated allelic-bursting shape dynamic random monoallelic expression in pregastrulation embryos
Recently, allele-specific single-cell RNA-seq analysis has demonstrated widespread dynamic random monoallelic expression of autosomal genes (aRME) in different cell types. However, the prevalence of dynamic aRME during pregastrulation remains unknown. Here, we show that dynamic aRME is widespread in...
Autores principales: | Naik, Hemant Chandru, Hari, Kishore, Chandel, Deepshikha, Mandal, Susmita, Jolly, Mohit Kumar, Gayen, Srimonta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379509/ https://www.ncbi.nlm.nih.gov/pubmed/34458702 http://dx.doi.org/10.1016/j.isci.2021.102954 |
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