Hyperactivity is a Core Endophenotype of Elevated Neuregulin-1 Signaling in Embryonic Glutamatergic Networks

The neuregulin 1 (NRG1) ErbB4 module is at the core of an “at risk” signaling pathway in schizophrenia. Several human studies suggest hyperstimulation of NRG1-ErbB4 signaling as a plausible pathomechanism; however, little is known about the significance of stage-, brain area-, or neural cell type-sp...

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Detalles Bibliográficos
Autores principales: Götze, Tilmann, Soto-Bernardini, Maria Clara, Zhang, Mingyue, Mießner, Hendrik, Linhoff, Lisa, Brzózka, Magdalena M, Velanac, Viktorija, Dullin, Christian, Ramos-Gomes, Fernanda, Peng, Maja, Husseini, Hümeyra, Schifferdecker, Eva, Fledrich, Robert, Sereda, Michael W, Willig, Katrin, Alves, Frauke, Rossner, Moritz J, Nave, Klaus-Armin, Zhang, Weiqi, Schwab, Markus H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379540/
https://www.ncbi.nlm.nih.gov/pubmed/33871014
http://dx.doi.org/10.1093/schbul/sbab027

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