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Mass spectrometry-based direct detection of multiple types of protein thiol modifications in pancreatic beta cells under endoplasmic reticulum stress
Thiol-based post-translational modifications (PTMs) play a key role in redox-dependent regulation and signaling. Functional cysteine (Cys) sites serve as redox switches, regulated through multiple types of PTMs. Herein, we aim to characterize the complexity of thiol PTMs at the proteome level throug...
Autores principales: | Li, Xiaolu, Day, Nicholas J., Feng, Song, Gaffrey, Matthew J., Lin, Tai-Du, Paurus, Vanessa L., Monroe, Matthew E., Moore, Ronald J., Yang, Bin, Xian, Ming, Qian, Wei-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379693/ https://www.ncbi.nlm.nih.gov/pubmed/34425387 http://dx.doi.org/10.1016/j.redox.2021.102111 |
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