Whole-genome methylation analysis of testicular germ cells from cryptozoospermic men points to recurrent and functionally relevant DNA methylation changes

BACKGROUND: Several studies have reported an association between male infertility and aberrant sperm DNA methylation patterns, in particular in imprinted genes. In a recent investigation based on whole methylome and deep bisulfite sequencing, we have not found any evidence for such an association, b...

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Detalles Bibliográficos
Autores principales: Di Persio, Sara, Leitão, Elsa, Wöste, Marius, Tekath, Tobias, Cremers, Jann-Frederik, Dugas, Martin, Li, Xiaolin, zu Hörste, Gerd Meyer, Kliesch, Sabine, Laurentino, Sandra, Neuhaus, Nina, Horsthemke, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379757/
https://www.ncbi.nlm.nih.gov/pubmed/34419158
http://dx.doi.org/10.1186/s13148-021-01144-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379757/
https://www.ncbi.nlm.nih.gov/pubmed/34419158
http://dx.doi.org/10.1186/s13148-021-01144-z

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