Melatonin contributes to the hypertrophic differentiation of mesenchymal stem cell-derived chondrocytes via activation of the Wnt/β-catenin signaling pathway: Melatonin promotes MSC-derived chondrocytes hypertrophy

BACKGROUND: Hypertrophy is a critical process for chondrocyte differentiation and maturation during endochondral ossification, which is responsible for the formation of long bone and postnatal longitudinal growth. Increasing evidence suggests that melatonin, an indole hormone, plays a pivotal role i...

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Detalles Bibliográficos
Autores principales: Wang, Xuan, He, Tianwei, He, Lei, Yang, Bu, Liu, Zhongyu, Pang, Mao, Xie, Peigen, Zhang, Liangming, Rong, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379782/
https://www.ncbi.nlm.nih.gov/pubmed/34419165
http://dx.doi.org/10.1186/s13287-021-02536-x

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