Cargando…

Cirbp-PSD95 axis protects against hypobaric hypoxia-induced aberrant morphology of hippocampal dendritic spines and cognitive deficits

Hypobaric hypoxia (HH) is a typical characteristic of high altitude environment and causes a spectrum of pathophysiological effects, including headaches, gliovascular dysfunction and cognitive retardation. Here, we sought to understand the mechanisms underlying cognitive deficits under HH exposure....

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Yang, Lu, Huanyu, Liu, Ying, Zhao, Zaihua, Zhang, Qian, Xue, Chong, Zou, Yuankang, Cao, Zipeng, Luo, Wenjing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379783/ https://www.ncbi.nlm.nih.gov/pubmed/34419133 http://dx.doi.org/10.1186/s13041-021-00827-1

Ejemplares similares

Postsynaptic density protein 95 (PSD-95) is transported by KIF5 to dendritic regions
por: Yoo, Ki-Seo, et al.
Publicado: (2019)

Acute Inactivation of PSD-95 Destabilizes AMPA Receptors at Hippocampal Synapses
por: Yudowski, Guillermo A., et al.
Publicado: (2013)

Chemical shift assignments of the N-terminal domain of PSD95 (PSD95-NT)
por: Zhang, Yonghong, et al.
Publicado: (2021)

CD40L Reverse Signaling Influences Dendrite Spine Morphology and Expression of PSD-95 and Rho Small GTPases
por: Carriba, Paulina, et al.
Publicado: (2020)

Resetting Proteostasis of CIRBP with ISRIB Suppresses Neural Stem Cell Apoptosis under Hypoxic Exposure
por: Zou, Yuankang, et al.
Publicado: (2022)

The role of sex and ovarian hormones in hippocampal damage and cognitive deficits induced by chronic exposure to hypobaric hypoxia
por: Zhu, Dongyong, et al.
Publicado: (2022)

PSD95 Suppresses Dendritic Arbor Development in Mature Hippocampal Neurons by Occluding the Clustering of NR2B-NMDA Receptors
por: Bustos, Fernando J., et al.
Publicado: (2014)

Multiple axons and actions with PSD-95
por: Williams, Ruth
Publicado: (2008)

PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling
por: Nikonenko, Irina, et al.
Publicado: (2008)

Model of inter-spine dynamics of PSD-95 molecules and its application to synaptic plasticity
por: Tsigankov, Dmitry, et al.
Publicado: (2010)

FRET-FLIM Investigation of PSD95-NMDA Receptor Interaction in Dendritic Spines; Control by Calpain, CaMKII and Src Family Kinase
por: Doré, Kim, et al.
Publicado: (2014)

Durable fear memories require PSD-95
por: Fitzgerald, Paul J., et al.
Publicado: (2014)

FMRP: a triple threat to PSD-95
por: Westmark, Cara J.
Publicado: (2013)

Fragile X Mental Retardation Protein Mediates the Effects of Androgen on Hippocampal PSD95 Expression and Dendritic Spines Density/Morphology and Autism-Like Behaviors Through miR-125a
por: Chen, Huan, et al.
Publicado: (2022)

Cytosolic PSD-95 interactor alters functional organization of neural circuits and AMPA receptor signaling independent of PSD-95 binding
por: Rodriguez, Ana R., et al.
Publicado: (2021)

A Specific Nutrient Combination Attenuates the Reduced Expression of PSD-95 in the Proximal Dendrites of Hippocampal Cell Body Layers in a Mouse Model of Phenylketonuria
por: Bruinenberg, Vibeke M., et al.
Publicado: (2016)

Excitation Control: Balancing PSD-95 Function at the Synapse
por: Keith, Dove, et al.
Publicado: (2008)

Rapid Redistribution of Synaptic PSD-95 in the Neocortex In Vivo
por: Gray, Noah W, et al.
Publicado: (2006)

PSD-95 protects synapses from β-amyloid
por: Dore, Kim, et al.
Publicado: (2021)

Spine dynamics of PSD-95-deficient neurons in the visual cortex link silent synapses to structural cortical plasticity
por: Yusifov, Rashad, et al.
Publicado: (2021)

Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2
por: Sarowar, Tasnuva, et al.
Publicado: (2016)

A stochastic model describing transport of PSD-95 molecules in spiny dendrites provides the basis for synaptic plasticity
por: Tsigankov, Dmitry, et al.
Publicado: (2011)

Structural Modeling of Protein Interactions by Analogy: Application to PSD-95
por: Korkin, Dmitry, et al.
Publicado: (2006)

Clustering of neuronal potassium channels is independent of their interaction with PSD-95
por: Rasband, Matthew N., et al.
Publicado: (2002)

Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome
por: Cao, Cong, et al.
Publicado: (2013)

PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits
por: Broadhead, Matthew J., et al.
Publicado: (2016)

Neurodevelopmental Disorders Associated with PSD-95 and Its Interaction Partners
por: Levy, Amanda M., et al.
Publicado: (2022)

AAV-Mediated Overexpression of Neuroserpin in the Hippocampus Decreases PSD-95 Expression but Does Not Affect Hippocampal-Dependent Learning and Memory
por: Tsang, Vicky W. K., et al.
Publicado: (2014)

Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines
por: Padmanabhan, Pranesh, et al.
Publicado: (2019)

Distinct Structural Requirements for Clustering and Immobilization of K(+) Channels by PSD-95
por: Burke, Nancy A., et al.
Publicado: (1999)

Correction: Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome
Publicado: (2014)

Correction: Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome
por: Cao, Cong, et al.
Publicado: (2013)

Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes
por: Frank, René A. W., et al.
Publicado: (2017)

Non-genomic mechanisms mediate androgen-induced PSD95 expression
por: Zhang, Yizhou, et al.
Publicado: (2019)

Anchoring and Synaptic stability of PSD-95 is driven by ephrin-B3
por: Hruska, Martin, et al.
Publicado: (2015)

PSD-95 Serine 73 phosphorylation is not required for induction of NMDA-LTD
por: Nowacka, Agata, et al.
Publicado: (2020)

PSD-95: An Effective Target for Stroke Therapy Using Neuroprotective Peptides
por: Ugalde-Triviño, Lola, et al.
Publicado: (2021)

Long-term potentiation reconstituted with an artificial TARP/PSD-95 complex
por: Ravi, Anagh Sinha, et al.
Publicado: (2022)

Fuzzy supertertiary interactions within PSD-95 enable ligand binding
por: Hamilton, George L, et al.
Publicado: (2022)

Visual–spatial learning impairments are associated with hippocampal PSD-95 protein dysregulation in a mouse model of fragile X syndrome
por: Gandhi, Réno M., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_mtc9ctl6h4dtvpmutep4e46ku5