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S-acylation of SARS-CoV-2 spike protein: Mechanistic dissection, in vitro reconstitution and role in viral infectivity

S-acylation, also known as palmitoylation, is the most widely prevalent form of protein lipidation, whereby long-chain fatty acids get attached to cysteine residues facing the cytosol. In humans, 23 members of the zDHHC family of integral membrane enzymes catalyze this modification. S-acylation is c...

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Detalles Bibliográficos
Autores principales:	Puthenveetil, Robbins, Lun, Cheng Man, Murphy, R. Elliot, Healy, Liam B., Vilmen, Geraldine, Christenson, Eric T., Freed, Eric O., Banerjee, Anirban
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379822/ https://www.ncbi.nlm.nih.gov/pubmed/34428449 http://dx.doi.org/10.1016/j.jbc.2021.101112

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