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Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans
BACKGROUND: Sulfate modification of N-glycans is important for several biological functions such as clearance of pituitary hormones or immunoregulation. Yet, the prevalence of this N-glycan modification and its functions remain largely unexplored. Characterization of N-glycans bearing sulfate modifi...
Autores principales: | Chuzel, Léa, Fossa, Samantha L., Boisvert, Madison L., Cajic, Samanta, Hennig, René, Ganatra, Mehul B., Reichl, Udo, Rapp, Erdmann, Taron, Christopher H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379841/ https://www.ncbi.nlm.nih.gov/pubmed/34419057 http://dx.doi.org/10.1186/s12934-021-01652-w |
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