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Alpinia oxyphylla Miq extract reduces cerebral infarction by downregulating JNK-mediated TLR4/T3JAM- and ASK1-related inflammatory signaling in the acute phase of transient focal cerebral ischemia in rats

BACKGROUND: Post-ischemic inflammation is a crucial component in stroke pathology in the early phase of cerebral ischemia–reperfusion (I/R) injury. Inflammation caused by microglia, astrocytes, and necrotic cells, produces pro-inflammatory mediators and exacerbates cerebral I/R injury. This study ev...

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Detalles Bibliográficos
Autores principales:	Cheng, Chin-Yi, Chiang, Su-yin, Kao, Shung-Te, Huang, Shang-Chih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379872/ https://www.ncbi.nlm.nih.gov/pubmed/34419138 http://dx.doi.org/10.1186/s13020-021-00495-2

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