Hexokinases inhibit death receptor–dependent apoptosis on the mitochondria

Death receptor–mediated apoptosis requires the mitochondrial apoptosis pathway in many mammalian cells. In response to death receptor signaling, the truncated BH3-only protein BID can activate the proapoptotic BCL-2 proteins BAX and BAK and trigger the permeabilization of the mitochondria. BAX and B...

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Detalles Bibliográficos
Autores principales: Lauterwasser, Joachim, Fimm-Todt, Franziska, Oelgeklaus, Aline, Schreiner, Annabell, Funk, Kathrin, Falquez-Medina, Hugo, Klesse, Ramona, Jahreis, Günther, Zerbes, Ralf M., O'Neill, Katelyn, van der Laan, Martin, Luo, Xu, Edlich, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379972/
https://www.ncbi.nlm.nih.gov/pubmed/34385311
http://dx.doi.org/10.1073/pnas.2021175118

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