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Hydrogen bonding rearrangement by a mitochondrial disease mutation in cytochrome bc(1) perturbs heme b(H) redox potential and spin state

Hemes are common elements of biological redox cofactor chains involved in rapid electron transfer. While the redox properties of hemes and the stability of the spin state are recognized as key determinants of their function, understanding the molecular basis of control of these properties is challen...

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Detalles Bibliográficos
Autores principales: Kuleta, Patryk, Lasham, Jonathan, Sarewicz, Marcin, Ekiert, Iwona, Sharma, Vivek, Ekiert, Robert, Osyczka, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8379992/
https://www.ncbi.nlm.nih.gov/pubmed/34389670
http://dx.doi.org/10.1073/pnas.2026169118