COVID‐19 infection presenting as paroxysmal nocturnal hemoglobinuria

A diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) was elicited during acute COVID‐19 infection. COVID‐19 spike proteins trigger the alternative pathway of complement. Acute SARS‐CoV‐2 infection possibly expanded an existing PIG‐A mutation.

Detalles Bibliográficos
Autores principales: Hines, Adam, Hakim, Nausheen, Barrientos, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380091/
https://www.ncbi.nlm.nih.gov/pubmed/34457288
http://dx.doi.org/10.1002/ccr3.4636
Descripción
Sumario:A diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) was elicited during acute COVID‐19 infection. COVID‐19 spike proteins trigger the alternative pathway of complement. Acute SARS‐CoV‐2 infection possibly expanded an existing PIG‐A mutation.

Ejemplares similares