COVID‐19 infection presenting as paroxysmal nocturnal hemoglobinuria

A diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) was elicited during acute COVID‐19 infection. COVID‐19 spike proteins trigger the alternative pathway of complement. Acute SARS‐CoV‐2 infection possibly expanded an existing PIG‐A mutation.

Detalles Bibliográficos
Autores principales: Hines, Adam, Hakim, Nausheen, Barrientos, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380091/
https://www.ncbi.nlm.nih.gov/pubmed/34457288
http://dx.doi.org/10.1002/ccr3.4636
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author Hines, Adam
Hakim, Nausheen
Barrientos, Jacqueline
author_facet Hines, Adam
Hakim, Nausheen
Barrientos, Jacqueline
author_sort Hines, Adam
collection PubMed
description A diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) was elicited during acute COVID‐19 infection. COVID‐19 spike proteins trigger the alternative pathway of complement. Acute SARS‐CoV‐2 infection possibly expanded an existing PIG‐A mutation.
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spelling pubmed-83800912021-08-27 COVID‐19 infection presenting as paroxysmal nocturnal hemoglobinuria Hines, Adam Hakim, Nausheen Barrientos, Jacqueline Clin Case Rep Case Reports A diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) was elicited during acute COVID‐19 infection. COVID‐19 spike proteins trigger the alternative pathway of complement. Acute SARS‐CoV‐2 infection possibly expanded an existing PIG‐A mutation. John Wiley and Sons Inc. 2021-08-21 /pmc/articles/PMC8380091/ /pubmed/34457288 http://dx.doi.org/10.1002/ccr3.4636 Text en © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Hines, Adam
Hakim, Nausheen
Barrientos, Jacqueline
COVID‐19 infection presenting as paroxysmal nocturnal hemoglobinuria
title COVID‐19 infection presenting as paroxysmal nocturnal hemoglobinuria
title_full COVID‐19 infection presenting as paroxysmal nocturnal hemoglobinuria
title_fullStr COVID‐19 infection presenting as paroxysmal nocturnal hemoglobinuria
title_full_unstemmed COVID‐19 infection presenting as paroxysmal nocturnal hemoglobinuria
title_short COVID‐19 infection presenting as paroxysmal nocturnal hemoglobinuria
title_sort covid‐19 infection presenting as paroxysmal nocturnal hemoglobinuria
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380091/
https://www.ncbi.nlm.nih.gov/pubmed/34457288
http://dx.doi.org/10.1002/ccr3.4636
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