Gene Therapy for Rdh12-Associated Retinal Diseases Helps to Delay Retinal Degeneration and Vision Loss

PURPOSE: The aim of study was to establish Rdh12-associated inherited retinal disease (Rdh12-IRD) mouse model and to identify the best timepoint for gene therapy. METHODS: We induced retinal degeneration in Rdh12(−/−) mice using a bright light. We clarified the establishment of Rdh12-IRD mouse model...

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Detalles Bibliográficos
Autores principales: Bian, Jiaxin, Chen, Hongyu, Sun, Junhui, Cao, Yuqing, An, Jianhong, Pan, Qing, Qi, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380142/
https://www.ncbi.nlm.nih.gov/pubmed/34429587
http://dx.doi.org/10.2147/DDDT.S305378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380142/
https://www.ncbi.nlm.nih.gov/pubmed/34429587
http://dx.doi.org/10.2147/DDDT.S305378

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