Cargando…

The role of NKX2-5 gene polymorphisms in congenital heart disease (CHD): a systematic review and meta-analysis

BACKGROUND: The gene NKX2-5 is a key transcription factor that plays an essential role in normal cardiac development. Although some recent studies have studied the role of polymorphisms in the NKX2-5 gene in congenital heart diseases (CHDs), the results were not consistent and remained uncertain. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ashiq, Sana, Ashiq, Kanwal, Sabar, Muhammad Farooq
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380205/ https://www.ncbi.nlm.nih.gov/pubmed/34417931 http://dx.doi.org/10.1186/s43044-021-00199-w

Ejemplares similares

CHD4 is recruited by GATA4 and NKX2-5 to repress noncardiac gene programs in the developing heart
por: Robbe, Zachary L., et al.
Publicado: (2022)

Association of NKX2‐5, GATA4, and TBX5 polymorphisms with congenital heart disease in Egyptian children
por: Behiry, Eman G., et al.
Publicado: (2019)

Association between single-nucleotide polymorphisms of NKX2.5 and congenital heart disease in Chinese population: A meta-analysis
por: Chen, Huan, et al.
Publicado: (2022)

Expression of Sumoylation Deficient Nkx2.5 Mutant in Nkx2.5 Haploinsufficient Mice Leads to Congenital Heart Defects
por: Kim, Eun Young, et al.
Publicado: (2011)

Investigation of somatic NKX2-5 mutations in congenital heart disease
por: Draus, J M, et al.
Publicado: (2009)

Genetics of Congenital Heart Defects: The NKX2-5 Gene, a Key Player
por: Chung, Ill-Min, et al.
Publicado: (2016)

Determination of expression profile of p53 gene in different grades of breast cancer tissues by real time PCR
por: Sadia, Haleema, et al.
Publicado: (2020)

Association of NFKB1, NKX2-5, GATA4 and RANKL Gene Polymorphisms with Sporadic Congenital Heart Disease in Greek Patients
por: Aidinidou, L, et al.
Publicado: (2021)

Investigation of Somatic NKX2-5 Mutations in Chinese Children with Congenital Heart Disease
por: Zheng, Jiayi, et al.
Publicado: (2015)

Extracellular Matrix Disparities in an Nkx2-5 Mutant Mouse Model of Congenital Heart Disease
por: Bousalis, Deanna, et al.
Publicado: (2020)

Novel Point Mutations in the NKX2.5 Gene in Pediatric Patients with Non-Familial Congenital Heart Disease
por: Khatami, Mehri, et al.
Publicado: (2018)

NKX2-5 mutations causative for congenital heart disease retain functionality and are directed to hundreds of targets
por: Bouveret, Romaric, et al.
Publicado: (2015)

Association of Maternal Diabetes Mellitus and Polymorphisms of the NKX2.5 Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study
por: Zhao, Mingyi, et al.
Publicado: (2020)

Associations between Two Genetic Variants in NKX2-5 and Risk of Congenital Heart Disease in Chinese Population: A Meta-Analysis
por: Wang, Zhenling, et al.
Publicado: (2013)

Infective endocarditis post-transcatheter aortic valve implantation (TAVI), microbiological profile and clinical outcomes: A systematic review
por: Khan, Adnan, et al.
Publicado: (2020)

Analysis of the CHD7 gene mutations in patients of congenital heart disease with extracardiac malformations
por: Huang, Xianghui, et al.
Publicado: (2023)

Nkx2.5+ Cardiomyoblasts Contribute to Cardiomyogenesis in the Neonatal Heart
por: Serpooshan, Vahid, et al.
Publicado: (2017)

Nuclear Receptor-Like Structure and Interaction of Congenital Heart Disease-Associated Factors GATA4 and NKX2-5
por: Kinnunen, Sini, et al.
Publicado: (2015)

Variations of CITED2 Are Associated with Congenital Heart Disease (CHD) in Chinese Population
por: Liu, Yan, et al.
Publicado: (2014)

SDF4CHD: Generative Modeling of Cardiac Anatomies with Congenital Heart Defects
por: Kong, Fanwei, et al.
Publicado: (2023)

Combined Mutation Screening of NKX2-5, GATA4, and TBX5 in Congenital Heart Disease: Multiple Heterozygosity and Novel Mutations
por: Granados-Riveron, Javier T, et al.
Publicado: (2012)

A comprehensive in silico analysis, distribution and frequency of human Nkx2-5 mutations; A critical gene in congenital heart disease
por: Kalayinia, Samira, et al.
Publicado: (2019)

Methyl 5-bromo-2-hydroxybenzoate
por: Mustafa, Ghulam, et al.
Publicado: (2012)

Solvothermally designed Pr-MOF/Fe(2)O(3) based nanocomposites for efficient electrocatalytic water splitting
por: Shabbir, Bushra, et al.
Publicado: (2023)

Berberis lyceum root bark extract attenuates anticancer drugs induced neurotoxicityand cardiotoxicity in rats
por: Qurat-ul-Ain, Sidra, et al.
Publicado: (2022)

3,4,5-Trihydroxybenzohydrazide
por: Ashiq, Uzma, et al.
Publicado: (2011)

Transformation of libraries during Covid-19 pandemic: A systematic review
por: Ashiq, Murtaza, et al.
Publicado: (2022)

The Ambiguous Role of NKX2-5 Mutations in Thyroid Dysgenesis
por: van Engelen, Klaartje, et al.
Publicado: (2012)

Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function
por: Dupays, Laurent, et al.
Publicado: (2019)

Abnormal uterine bleeding in a female with Klippel Trenaunay syndrome
por: Pramchand, Ashiq
Publicado: (2022)

The Role of Genetic Polymorphism and Other Factors on Clopidogrel Resistance (CR) in an Asian Population with Coronary Heart Disease (CHD)
por: Akkaif, Mohammed Ahmed, et al.
Publicado: (2021)

Mutations in the 3'-untranslated region of GATA4 as molecular hotspots for congenital heart disease (CHD)
por: Reamon-Buettner, Stella Marie, et al.
Publicado: (2007)

Early Results of the Persian Registry of Cardiovascular Disease/Congenital Heart Disease (PROVE/CHD) in Isfahan
por: Ahmadi, Ali Reza, et al.
Publicado: (2020)

Impact of cardiac surgical timing on the neurodevelopmental outcomes of newborns with Complex congenital heart disease (CHD)
por: Lenoir, Marien, et al.
Publicado: (2023)

Genetic risk score (GRS) constructed from polymorphisms in the PON1, IL-6, ITGB3, and ALDH2 genes is associated with the risk of coronary artery disease in Pakistani subjects
por: Shabana, NA, et al.
Publicado: (2018)

The roles of MTRR and MTHFR gene polymorphisms in congenital heart diseases: a meta-analysis
por: Xu, Aiping, et al.
Publicado: (2018)

The single-nucleotide polymorphisms in CHD5 affect the prognosis of patients with hepatocellular carcinoma
por: Zhu, Xiao, et al.
Publicado: (2017)

Potential of Biological Agents in Decontamination of Agricultural Soil
por: Javaid, Muhammad Kashif, et al.
Publicado: (2016)

Nkx2.7 and Nkx2.5 Function Redundantly and Are Required for Cardiac Morphogenesis of Zebrafish Embryos
por: Tu, Chi-Tang, et al.
Publicado: (2009)

CHD7 gene polymorphisms in female patients with idiopathic scoliosis
por: Borysiak, Karolina, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2cckr11itujjun9nchpe4dot4q