Cargando…
Physiology-based toxicokinetic modelling of aluminium in rat and man
A sufficient quantitative understanding of aluminium (Al) toxicokinetics (TK) in man is still lacking, although highly desirable for risk assessment of Al exposure. Baseline exposure and the risk of contamination severely limit the feasibility of TK studies administering the naturally occurring isot...
Autores principales: | Hethey, Christoph, Hartung, Niklas, Wangorsch, Gaby, Weisser, Karin, Huisinga, Wilhelm |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380244/ https://www.ncbi.nlm.nih.gov/pubmed/34390355 http://dx.doi.org/10.1007/s00204-021-03107-y |
Ejemplares similares
-
Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine (TETS) in mice
por: Pressly, Brandon, et al.
Publicado: (2020) -
PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat
por: Lehmann, Anja, et al.
Publicado: (2023) -
Toxicokinetics of U-47700, tramadol, and their main metabolites in pigs following intravenous administration: is a multiple species allometric scaling approach useful for the extrapolation of toxicokinetic parameters to humans?
por: Nordmeier, Frederike, et al.
Publicado: (2021) -
Inter-individual variation in chlorpyrifos toxicokinetics characterized by physiologically based kinetic (PBK) and Monte Carlo simulation comparing human liver microsome and Supersome(™) cytochromes P450 (CYP)-specific kinetic data as model input
por: Zhao, Shensheng, et al.
Publicado: (2022) -
Physiologically based kinetic modelling based prediction of in vivo rat and human acetylcholinesterase (AChE) inhibition upon exposure to diazinon
por: Zhao, Shensheng, et al.
Publicado: (2021)